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wobina

Gabapentin and b3nz0s (cross tolerance?)

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wobina

Is this a thing? Could anyone with experience tell me if there's a cross-tolerance between gabapentin and b3nz0s (like kplnz)? I've been down the b3nz0 dependence road before and would prefer not to go down it again. I use both gabapentin and kpln sparingly but I'd like to know how they interact...

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sweetmelissa589

I use both and have not noticed any cross-tolerance issues at all.   I know that gabapentin does not bind to gaba receptors like benzOs do, so it should be fine..  Coming off gabapentin was hell though and I'll never take it daily again.  I stick with twice a week, same with the alps I take..

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sweetmelissa589

It's hard to say..  To give you an idea, I was taking 400mg, 3 times daily for 4 months.  I did a very long and slow taper and still suffered.  The insomnia and anxiety were the worst.

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fbulb

Wow I need to get off the gaba then. Have you had the same experience with lyrica? I am supposed to get it whenever the insurance feels like authorizing it

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sweetmelissa589

I was on Gab@ for like 6 months 400mg a day only and it was hell coming off of.  Severe anxiety, insomnia and paranoia for months...  It took about 5 months, maybe longer to get back to normal.  I still have 100's left and won't touch them.

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Dickslapperman

@sweetmelissa589 that's weird I had a long run with them and the withdrawal was pretty easy compared to anything else maby like 5 days of sweating irritability and restless legs after that was completely over with I guess everyone is differentm

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sweetmelissa589

@Dickslapperman   True.. I guess everyone is different.  When I used to go to the mth@don3 cliic, I would be so sick and could hardly even get dressed the next day to go get my other d0se.  I thought this was normal.  Then one day as I was waiting in line to d0se, I heard someone say that they forgot to take their  d0se yesterday.   I couldn'e believe it, because the day I took my d0se, I would start to feel bad around 6:00pm. with yawning and goosebumps, skin scrawling and couldn't sleep at all,  so I was amazed to see this girl forgot to even take hers...lol.  Anyway,  I just couldn't handle being sick everyday and switched to subs, which are great because I can d0se as needed.  I hate them though.  I have been on them for 4 years and now I have anhedonia.  I get no pleasure out of anything and am trying to taper off of them.  I have turned to rc b3nz0s to help me taper, but I think I'm making the problem worse, as I'm an @ddicit and now I have 2 @dicitions..    Anyway.. sorry for the long sorry..lol.. 

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porkandbeansboy

They have ZERO cross Tolerance... they even use G@BAPentin in B3nzodi@zepine Withdrawal due to this fact and same with Baclofen since it only affects G@BA-B and not the G@BA-A Sub Units that B3nz0s affect. I use GABAPentin for sleep with Baclofen everynight because my Daily use of B3nz0s only allows Me to use it once a week at a higher D0se for effects. When I do get effects the next Day I can feel my Tolerance rise so rapidly that I feel less than 50% of the effects the D@y before but the problem is the only way to lower B3nz0 Tolerance is to use less of them D@ily and for a LONG time like I said only once a week I use a higher D0se and it only has a better effect for one single D@y 2 at most and at higher D0ses. 

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